Cyclopentane, as a blowing agent, provides excellent thermal insulation and good foam physical properties while meeting excellent environmental standards (ODP = 0, extremely low GWP), all while maintaining a very competitive cost.

| Blowing Agent Type | Representative Substances | ODP | GWP | Main Advantages and Disadvantages |
| First Generation (CFCs) | CFC-11 | Very High (1.0) | Very High (4750) | Phased Out. Depletes the ozone layer. |
| Transitional (HCFCs) | HCFC-141b | Low (0.11) | High (725) | Phasing Out. Still depletes the ozone layer and has a high GWP |
| Second Generation (HFCs) | HFC-245fa, HFC-365mfc | 0 | High (~800-1000) | Does not deplete the ozone layer, but has a high GWP and faces pressure to be phased out. High cost. |
| Hydrocarbons (HCs) | Cyclopentane | 0 | Very low (~11) | Excellent environmental performance, low cost. However, it is flammable. |
| Hydrogenated Olefins (HFOs) | HFO-1234ze | 0 | Very low (<1) | A new generation of environmentally friendly products with excellent ODP and GWP. However, it is very expensive and currently mainly used in high-end or specialized applications. |
| Liquid CO₂ | CO₂ | 0 | 1 (itself) | Extremely environmentally friendly, safe, and non-flammable. However, the resulting foam has a high thermal conductivity (slightly lower thermal insulation performance), requiring high processing and equipment requirements. |

The thermal insulation performance of expanded plastics (such as rigid polyurethane foam) depends primarily on the thermal conductivity of the gas (blowing agent) within the foam pores. Cyclopentane's low vapor-phase thermal conductivity effectively blocks heat transfer, resulting in highly efficient foam insulation. It is widely used in the insulation of household appliances (such as refrigerators and freezers).

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